Non sedating muscle relaxant

30-Jul-2015 19:52 by 2 Comments

Non sedating muscle relaxant - totaly local online dating

Tricyclic anti-depressants that are commonly used in the treatment of fibromyalgia include Amitriptyline (Elavil), Nortriptyline (Pamelor), and Doxepin (Sinequan).Amitriptyline is perhaps the most common as its efficacy has been demonstrated in controlled studies and it is known to enhance stage 3 and 4 sleep.

Fibromyalgia patients seem especially sensitive to these side effects.Therefore, the dose should be individualized and generally begun at the lowest possible dose (such as 5 to 10 mg) at nighttime.Taking the drug 1 to 2 hours prior to sleep can minimize difficulties with morning sedation or "hangover".If there is no response, the dose can increase after 2 to 3 weeks.Muscle relaxants such as Cyclobenzaprine (Flexeril) and Orphenadrine Citrate (Norflex) have also been studied in the treatment of fibromyalgia.Cyclobenzaprine has a tricyclic chemical structure similar to Amitriptyline, yet its anti-depressant effects are minimal. In a study of 120 fibromyalgia patients, those receiving Cyclobenzaprine (10 to 40 mg) over a 12 week period had significantly improved quality of sleep and pain score.

There was a trend towards improvement in fatigue symptoms but not in duration of morning stiffness.Interestingly, there was also a reduction in the total number of tender points and muscle tightness.For use in treating fibromyalgia, common beginning dosages are generally 5 to 10 mg at bedtime.Again, common side effects include dry mouth, drowsiness, and constipation.Orphenadrine Citrate (Norflex) is a centrally acting analgesic muscle relaxant.It is used as an adjunct to rest, physical therapy and symptomatic measures for acute musculoskeletal pain.

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